TRACK RECORDS
Background
After a mathematical M.Sc. and a Ph.D. thesis in Biology, Jerome Wojcik joined Hybrigenics, a start-up biotech company based in Paris, where he managed during 6 years the bioinformatics and IT department. He then joined Serono (now Merck Serono) in Geneva where he was in charge of a team of bioinformatics scientists developing algorithms adapted to genome-wide genetic association studies. The scope extended quickly to genomics and to biomarkers in general (proteomics, flow cytometry and imaging), leading to the creation of a centralized “Stratified Medicine” department within the organization, regrouping clinical project leaders, labs and bioinformatics.
After 7 years of experience in the pharmaceutical industry, Jerome Wojcik left his position of Director of Global Bioinformatics of Merck Serono to create his own company, Quartz Bio, a clinical bioinformatics service company supporting biotech and pharmaceutical companies in the implementation of their Precision Medicine strategies by performing reproducible exploratory biomarker data analyses. In October 2017, Quartz Bio joined Precision for Medicine to become its European Translational Informatics and Biometrics group. Once the integration was complete, Jerome Wojcik joined STALICLA as Managing Director and Head of Data Sciences and Diagnostics to structure their bioinformatics team and initiate the creation of a non-profit Foundation in Neurodegenerative Disorders.
Jerome Wojcik is currently Managing Partner of Data2time, a life data science consulting company aiming at making data save time.
Case studies
Jerome Wojcik managed the exploratory statistical analyses of over 250 clinical trials, from phase I to phase IV, in various therapeutic areas (oncology, immunology, neurology, endocrinology, ophthalmology, fertility, and rare diseases) and was involved as a principal data scientist in over 50 of them.
He also lead the data management and data analysis work package of the PRECISESADS Innovative Medicines Initiative [IMI] consortium, a European collaborative involving 23 research centres and five companies from 12 European countries, with the ultimate goal to find innovative diagnostic technology to relate systemic autoimmune diseases [SAD] to detectable changes in individual molecular signatures.
Jerome Wojcik is also Chairman of the Board of Directors of the Swiss Institute of Bioinformatics (SIB), former member of the Scientific Advisory Board [SAB] of ELIXIR, former member of the Industrial Advisory Committee of the French Institute of Bioinformatics, and occasional bioinformatics lecturer at the University of Lausanne [UNIL].
Publications
Oncology
- Custom scoring based on ecological topology of gut microbiota associated with cancer immunotherapy outcome DOI Cell, 2024
Immunology
- Patients with Optimized Hemophagocytic Lymphohistiocytosis (HLH) Inflammatory (OHI) Index-Confirmed Diagnosis of Malignancy-Associated HLH (mHLH) and Emapalumab Treatment DOI Blood 2024
- Pharmacodynamic biomarkers of long-term interferon beta-1a therapy in REFLEX and REFLEXION DOI Journal of Neuroimmunology, 2021
- Integrative analysis reveals a molecular stratification of systemic autoimmune diseases DOI Arthritis & rheumatology, 2021
- Pharmacodynamic Biomarkers of Interferon β-1a: Assessment in Patients Receiving Long-Term Treatment with Subcutaneous Interferon β-1a DOI Neurology, 2020
Neurodegenerative diseases
- Blood‐based multi‐omic signatures of blood‐brain barrier impairment and CSF‐defined Alzheimer disease in older adults DOI Alzheimer’s & Dementia, 2021
- Blood‐brain barrier breakdown, neuroinflammation, and cognitive decline in older adults DOI Alzheimer’s & Dementia, 2018
- Proteomes of paired human cerebrospinal fluid and plasma: relation to blood–brain barrier permeability in older adults DOI Journal of proteome research, 2019
- One-carbon metabolism, cognitive impairment and CSF measures of Alzheimer pathology: homocysteine and beyond DOI Alzheimer’s research & therapy, 2017
- Markers of neuroinflammation associated with Alzheimer’s disease pathology in older adults DOI Brain, behavior, and immunity, 2017
Endocrinology
- Validating genetic markers of response to recombinant human growth hormone (r-hGH) in children with growth hormone deficiency (GHD) and Turner Syndrome (TS): The PREDICT Validation study DOI European Journal of Endocrinology, 2016
- GH deficiency status combined with GH receptor polymorphism affects response to GH in children DOI European Journal of Endocrinology, 2015
Other
- Artificial intelligence for individualized treatment of persistent atrial fibrillation: a randomized controlled trial DOI Nature Medicine, 2025
- Equivalency of EPA and DHA Bioavailability When Comparing Microalgal and Fish Oil Supplementation DOI Current Developments in Nutrition, 2024
- Protective effects of rimeporide on left ventricular function in golden retriever muscular dystrophy dogs DOI International Journal of Cardiology, 2020